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A typical diploid human cell preparing to divide copies roughly six billion base pairs of nuclear DNA. Each daughter cell needs a complete set. An error at every thousandth base would leave extensive damage, while the illustrative final error rate used here is about one per billion after correction.
A typical diploid human nucleus is only a few micrometers wide. Before replication, its DNA would stretch roughly two meters. The cell must pack that DNA, expose selected genes for reading, and copy it accurately before division. Start with the nucleotide: its sugar, phosphate, and base explain how
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