RT Journal Article
SR Electronic
T1 Expression-Based Cell Lineage Analysis in *Drosophila* Through a Course-Based Research Experience for Early Undergraduates
JF G3: Genes|Genomes|Genetics
FD Genetics Society of America
SP 3791
OP 3800
DO 10.1534/g3.119.400541
VO 9
IS 11
A1 Olson, John M.
A1 Evans, Cory J.
A1 Ngo, Kathy T.
A1 Kim, Hee Jong
A1 Nguyen, Joseph Duy
A1 Gurley, Kayla G. H.
A1 Ta, Truc
A1 Patel, Vijay
A1 Han, Lisa
A1 Truong-N, Khoa T.
A1 Liang, Letty
A1 Chu, Maggie K.
A1 Lam, Hiu
A1 Ahn, Hannah G.
A1 Banerjee, Abhik Kumar
A1 Choi, In Young
A1 Kelley, Ross G.
A1 Moridzadeh, Naseem
A1 Khan, Awais M.
A1 Khan, Omair
A1 Lee, Szuyao
A1 Johnson, Elizabeth B.
A1 Tigranyan, Annie
A1 Wang, Jay
A1 Gandhi, Anand D.
A1 Padhiar, Manish M.
A1 Calvopina, Joseph Hargan
A1 Sumra, Kirandeep
A1 Ou, Kristy
A1 Wu, Jessie C.
A1 Dickan, Joseph N.
A1 Ahmadi, Sabrena M.
A1 Allen, Donald N.
A1 Mai, Van Thanh
A1 Ansari, Saif
A1 Yeh, George
A1 Yoon, Earl
A1 Gon, Kimberly
A1 Yu, John Y.
A1 He, Johnny
A1 Zaretsky, Jesse M.
A1 Lee, Noemi E.
A1 Kuoy, Edward
A1 Patananan, Alexander N.
A1 Sitz, Daniel
A1 Tran, PhuongThao
A1 Do, Minh-Tu
A1 Akhave, Samira J.
A1 Alvarez, Silverio D.
A1 Asem, Bobby
A1 Asem, Neda
A1 Azarian, Nicole A.
A1 Babaesfahani, Arezou
A1 Bahrami, Ahmad
A1 Bhamra, Manjeet
A1 Bhargava, Ragini
A1 Bhatia, Rakesh
A1 Bhatia, Subir
A1 Bumacod, Nicholas
A1 Caine, Jonathan J.
A1 Caldwell, Thomas A.
A1 Calica, Nicole A.
A1 Calonico, Elise M.
A1 Chan, Carman
A1 Chan, Helen H.-L.
A1 Chang, Albert
A1 Chang, Chiaen
A1 Chang, Daniel
A1 Chang, Jennifer S.
A1 Charania, Nauman
A1 Chen, Jasmine Y.
A1 Chen, Kevin
A1 Chen, Lu
A1 Chen, Yuyu
A1 Cheung, Derek J.
A1 Cheung, Jesse J.
A1 Chew, Jessica J.
A1 Chew, Nicole B.
A1 Chien, Cheng-An Tony
A1 Chin, Alana M.
A1 Chin, Chee Jia
A1 Cho, Youngho
A1 Chou, Man Ting
A1 Chow, Ke-Huan K.
A1 Chu, Carolyn
A1 Chu, Derrick M.
A1 Chu, Virginia
A1 Chuang, Katherine
A1 Chugh, Arunit Singh
A1 Cubberly, Mark R.
A1 Daniel, Michael Guillermo
A1 Datta, Sangita
A1 Dhaliwal, Raj
A1 Dinh, Jenny
A1 Dixit, Dhaval
A1 Dowling, Emmylou
A1 Feng, Melinda
A1 From, Christopher M.
A1 Furukawa, Daisuke
A1 Gaddipati, Himaja
A1 Gevorgyan, Lilit
A1 Ghaznavi, Zunera
A1 Ghosh, Tulika
A1 Gill, Jaskaran
A1 Groves, David J.
A1 Gurara, Kalkidan K.
A1 Haghighi, Ali R.
A1 Havard, Alexandra L.
A1 Heyrani, Nasser
A1 Hioe, Tanya
A1 Hong, Kirim
A1 Houman, Justin J.
A1 Howland, Molly
A1 Hsia, Elaine L.
A1 Hsueh, Justin
A1 Hu, Stacy
A1 Huang, Andrew J.
A1 Huynh, Jasmine C.
A1 Huynh, Jenny
A1 Iwuchukwu, Chris
A1 Jang, Michael J.
A1 Jiang, An An
A1 Kahlon, Simran
A1 Kao, Pei-Yun
A1 Kaur, Manpreet
A1 Keehn, Matthew G.
A1 Kim, Elizabeth J.
A1 Kim, Hannah
A1 Kim, Michelle J.
A1 Kim, Shawn J.
A1 Kitich, Aleksandar
A1 Kornberg, Ross A.
A1 Kouzelos, Nicholas G.
A1 Kuon, Jane
A1 Lau, Bryan
A1 Lau, Roger K.
A1 Law, Rona
A1 Le, Huy D.
A1 Le, Rachael
A1 Lee, Carrou
A1 Lee, Christina
A1 Lee, Grace E.
A1 Lee, Kenny
A1 Lee, Michelle J.
A1 Lee, Regina V.
A1 Lee, Sean H. K.
A1 Lee, Sung Kyu
A1 Lee, Sung-Ling D.
A1 Lee, Yong Jun
A1 Leong, Megan J.
A1 Li, David M.
A1 Li, Hao
A1 Liang, Xingfu
A1 Lin, Eric
A1 Lin, Michelle M.
A1 Lin, Peter
A1 Lin, Tiffany
A1 Lu, Stacey
A1 Luong, Serena S.
A1 Ma, Jessica S.
A1 Ma, Li
A1 Maghen, Justin N.
A1 Mallam, Sravya
A1 Mann, Shivtaj
A1 Melehani, Jason H.
A1 Miller, Ryan C.
A1 Mittal, Nitish
A1 Moazez, Carmel M.
A1 Moon, Susie
A1 Moridzadeh, Rameen
A1 Ngo, Kaley
A1 Nguyen, Hanh H.
A1 Nguyen, Kambria
A1 Nguyen, Thien H.
A1 Nieh, Angela W.
A1 Niu, Isabella
A1 Oh, Seo-Kyung
A1 Ong, Jessica R.
A1 Oyama, Randi K.
A1 Park, Joseph
A1 Park, Yaelim A.
A1 Passmore, Kimberly A.
A1 Patel, Ami
A1 Patel, Amy A.
A1 Patel, Dhruv
A1 Patel, Tirth
A1 Peterson, Katherine E.
A1 Pham, An Huynh
A1 Pham, Steven V.
A1 Phuphanich, Melissa E.
A1 Poria, Neil D.
A1 Pourzia, Alexandra
A1 Ragland, Victoria
A1 Ranat, Riki D.
A1 Rice, Cameron M.
A1 Roh, David
A1 Rojhani, Solomon
A1 Sadri, Lili
A1 Saguros, Agafe
A1 Saifee, Zainab
A1 Sandhu, Manjot
A1 Scruggs, Brooke
A1 Scully, Lisa M.
A1 Shih, Vanessa
A1 Shin, Brian A.
A1 Sholklapper, Tamir
A1 Singh, Harnek
A1 Singh, Sumedha
A1 Snyder, Sondra L.
A1 Sobotka, Katelyn F.
A1 Song, Sae Ho
A1 Sukumar, Siddharth
A1 Sullivan, Halley C.
A1 Sy, Mark
A1 Tan, Hande
A1 Taylor, Sara K.
A1 Thaker, Shivani K.
A1 Thakore, Tulsi
A1 Tong, Gregory E.
A1 Tran, Jacinda N.
A1 Tran, Jonathan
A1 Tran, Tuan D.
A1 Tran, Vivi
A1 Trang, Cindy L.
A1 Trinh, Hung G.
A1 Trinh, Peter
A1 Tseng, Han-Ching H.
A1 Uotani, Ted T.
A1 Uraizee, Akram V.
A1 Vu, Kent K. T.
A1 Vu, Kevin K. T.
A1 Wadhwani, Komal
A1 Walia, Paluk K.
A1 Wang, Rebecca S.
A1 Wang, Shuo
A1 Wang, Stephanie J.
A1 Wiredja, Danica D.
A1 Wong, Andrew L.
A1 Wu, Daniel
A1 Xue, Xi
A1 Yanez, Griselda
A1 Yang, Yung-Hsuan
A1 Ye, Zhong
A1 Yee, Victor W.
A1 Yeh, Cynthia
A1 Zhao, Yue
A1 Zheng, Xin
A1 Ziegenbalg, Anke
A1 Alkali, Jon
A1 Azizkhanian, Ida
A1 Bhakta, Akash
A1 Berry, Luke
A1 Castillo, Ryen
A1 Darwish, Sonja
A1 Dickinson, Holly
A1 Dutta, Ritika
A1 Ghosh, Rahul Kumar
A1 Guerin, Riley
A1 Hofman, Jonathan
A1 Iwamoto, Garrick
A1 Kang, Sarah
A1 Kim, Andrew
A1 Kim, Brian
A1 Kim, Hanwool
A1 Kim, Kristine
A1 Kim, Suji
A1 Ko, Julie
A1 Koenig, Michael
A1 LaRiviere, Alejandro
A1 Lee, Clifton
A1 Lee, Jiwon
A1 Lung, Brandon
A1 Mittelman, Max
A1 Murata, Mark
A1 Park, Yujin
A1 Rothberg, Daniel
A1 Sprung-Keyser, Ben
A1 Thaker, Kunal
A1 Yip, Vivian
A1 Picard, Paul
A1 Diep, Francie
A1 Villarasa, Nikki
A1 Hartenstein, Volker
A1 Shapiro, Casey
A1 Levis-Fitzgerald, Marc
A1 Jaworski, Leslie
A1 Loppato, David
A1 Clark, Ira E.
A1 Banerjee, Utpal
YR 2019
UL http://www.g3journal.org/content/9/11/3791.abstract
AB A variety of genetic techniques have been devised to determine cell lineage relationships during tissue development. Some of these systems monitor cell lineages spatially and/or temporally without regard to gene expression by the cells, whereas others correlate gene expression with the lineage under study. The GAL4 Technique for Real-time and Clonal Expression (G-TRACE) system allows for rapid, fluorescent protein-based visualization of both current and past GAL4 expression patterns and is therefore amenable to genome-wide expression-based lineage screens. Here we describe the results from such a screen, performed by undergraduate students of the University of California, Los Angeles (UCLA) Undergraduate Research Consortium for Functional Genomics (URCFG) and high school summer scholars as part of a discovery-based education program. The results of the screen, which reveal novel expression-based lineage patterns within the brain, the imaginal disc epithelia, and the hematopoietic lymph gland, have been compiled into the G-TRACE Expression Database (GED), an online resource for use by the Drosophila research community. The impact of this discovery-based research experience on student learning gains was assessed independently and shown to be greater than that of similar programs conducted elsewhere. Furthermore, students participating in the URCFG showed considerably higher STEM retention rates than UCLA STEM students that did not participate in the URCFG, as well as STEM students nationwide.