HOMA-IR Calculator

Estimate insulin resistance from fasting glucose and fasting insulin using HOMA-IR, and see the matching beta-cell function (HOMA-B). Example: fasting glucose 95 mg/dL and insulin 10 uIU/mL give a HOMA-IR of 2.3.

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Glucose units

Fasting glucose

Fasting insulin (uIU/mL)

How to use the HOMA-IR Calculator

Enter the values in the fields.
Press Calculate to see the result with the steps shown.

Formula and method

HOMA-IR = fasting glucose (mmol/L) x fasting insulin (uIU/mL) / 22.5. With mg/dL: glucose x insulin / 405. HOMA-B = 20 x insulin / (glucose – 3.5).

HOMA-IR categories

HOMA-IR	Common reading
Below 1.0	Optimal insulin sensitivity
1.0 to 1.9	Normal
1.9 to 2.9	Early insulin resistance
3.0 and above	Significant insulin resistance

Example values

Glucose (mg/dL)	Insulin	HOMA-IR
85	5	1.05
95	10	2.35
105	15	3.89
120	20	5.93

How to prepare for the test

Fast overnight for 8 to 12 hours, avoid hard exercise the day before and take the glucose and insulin from the same blood draw.

Limits

This calculator is for education and is not medical advice. Decisions about testing and treatment belong with a qualified clinician.

Frequently asked questions

What is a good HOMA-IR?

Below about 1.0 to 2.0 is generally favorable.

What is the cutoff for insulin resistance?

Roughly 2.5 to 3.0, depending on the study.

How is HOMA-IR calculated?

Glucose times insulin divided by 405 (mg/dL) or 22.5 (mmol/L).

Do I need to fast?

Yes, 8 to 12 hours.

Can I lower it?

Weight loss, exercise and sleep improve insulin sensitivity.

Is it diagnostic?

No.

Sources

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