Creatinine Clearance Calculator (Cockcroft-Gault)

Estimate creatinine clearance with the Cockcroft-Gault equation using actual, ideal and adjusted body weight. Example: a 60-year-old man, 80 kg, serum creatinine 1.0 mg/dL has a clearance of about 89 mL/min.

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How to use the Creatinine Clearance Calculator (Cockcroft-Gault)

  1. Enter the values in the fields.
  2. Press Calculate to see the result with the steps shown.

Formula and method

CrCl (mL/min) = (140 – age) x weight (kg) / (72 x serum creatinine in mg/dL), multiplied by 0.85 for women.

Kidney function ranges

CrCl (mL/min) Interpretation
90 and above Normal
60 to 89 Mildly reduced
30 to 59 Moderately reduced
15 to 29 Severely reduced
Below 15 Kidney failure range

Which weight to use

Actual weight works for people near ideal weight. If actual weight is more than 120 to 130% of ideal, many references use adjusted weight; for underweight patients use actual. Practice varies, so this tool shows all three.

Cockcroft-Gault versus eGFR

Cockcroft-Gault estimates a clearance in mL/min and is not indexed to body size, while CKD-EPI eGFR is indexed to 1.73 m2. Drug labels often use CrCl, and kidney staging uses eGFR.

Cautions

This calculator is for education and is not medical advice. Lab and clinical decisions belong with a qualified clinician who sees the whole picture.

Frequently asked questions

What is creatinine clearance?

The volume of blood cleared of creatinine per minute, a kidney function estimate.

What is the Cockcroft-Gault formula?

(140 – age) x weight / (72 x creatinine), times 0.85 for women.

Which weight should I use?

Often actual, ideal or adjusted depending on body size and policy.

Normal creatinine clearance?

About 90 to 120 mL/min in young adults, declining with age.

CrCl or eGFR?

Use CrCl for many drug doses and eGFR for staging chronic kidney disease.

Does it work in children?

No.

Sources

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